| 25 (9-2) Texas A&M vs. 229 (2-7) Houston Christian | 2:00 PM | Reed Arena, College Station, TX | ESPN+ | 84 - 56 | 94% | | |
| 31 (9-2) Dayton vs. 38 (8-1) Cincinnati* | 8:30 PM | Heritage Bank Center, Cincinnati, OH | | 74 - 69 | 55% | | |
| 48 (8-2) BYU vs. 313 (1-6) Florida A&M | 9:00 PM | Marriott Center, Provo, UT | ESPN+ | 89 - 60 | 87% | | |
| 84 (5-3) North Texas vs. 178 (4-5) Appalachian St | 8:00 PM | The Super Pit, Denton, TX | ESPN+ | 70 - 58 | 84% | | |
| 127 (4-5) Yale vs. 138 (4-3) Akron* | 7:00 PM | Don Haskins Center, El Paso, TX | | 83 - 77 | 72% | | |
| 129 (7-5) Providence vs. 1 (9-2) St. Johns | 8:00 PM | Amica Mutual Pavilion, Providence, RI | | 68 - 75 | 26% | | |
| 142 (5-3) UTEP vs. 336 (0-10) Jackson St | 9:00 PM | Don Haskins Center, El Paso, TX | | 82 - 62 | 86% | | |
| 187 (5-4) Loyola Mary vs. 285 (2-5) Southern | 10:00 PM | Gersten Pavilion, Los Angeles, CA | ESPN+ | 77 - 64 | 77% | | |
| 245 (2-7) Seattle vs. 216 (4-4) Illinois-Chicago | 5:00 PM | Redhawk Center, Seattle, WA | ESPN+ | 78 - 73 | 60% | | |
| 277 (2-7) W Michigan vs. 201 (4-5) Valparaiso | 1:00 PM | University Arena (MI), Kalamazoo, MI | ESPN+ | 73 - 75 | 38% | | |
| 279 (5-6) Siena vs. 289 (5-5) Holy Cross | 7:00 PM | MVP Arena, Albany, NY | ESPN+ | 72 - 66 | 70% | | |
| 288 (3-7) Alabama St vs. 321 (3-6) Delaware St* | 6:30 PM | Mohegan Sun Arena, Uncasville, CT | | 79 - 71 | 74% | | |
| 291 (3-8) N Carolina Cent vs. 192 (7-3) Longwood | 7:00 PM | McDougald-McLendon Arena, Durham, NC | ESPN+ | 73 - 74 | 34% | | |
| 304 (3-7) Pennsylvania vs. 274 (4-7) Rider | 6:00 PM | The Palestra, Philadelphia, PA | ESPN+ | 69 - 67 | 69% | | |
| 310 (3-5) St. Peters vs. 186 (5-4) Delaware | 7:00 PM | Yanitelli Center, Jersey City, NJ | ESPN+ | 71 - 75 | 34% | | |
| 357 (0-8) Grambling St vs. 236 (5-6) Norfolk St* | 4:00 PM | Mohegan Sun Arena, Uncasville, CT | | 69 - 74 | 32% | | |