| 5 (13-4) Michigan vs. 73 (11-6) Northwestern | 2:00 PM | Crisler Center, Ann Arbor, MI | Big Ten Network | 79 - 69 | 75% | | |
| 10 (15-2) Michigan St vs. 7 (13-4) Illinois | 12:00 PM | Breslin Center, East Lansing, MI | CBS | 78 - 73 | 56% | | |
| 65 (13-5) Maryland vs. 34 (12-5) Nebraska | 12:00 PM | XFINITY Center, College Park, MD | Big Ten Network | 75 - 73 | 47% | | |
| 74 (10-5) Baylor vs. 113 (9-7) TCU | 5:00 PM | Foster Pavilion, Waco, TX | ESPN | 75 - 68 | 73% | | |
| 109 (10-6) Temple vs. 137 (8-7) Tulane | 1:00 PM | Liacouras Center, Philadelphia, PA | | 78 - 70 | 76% | | |
| 132 (11-6) Milwaukee vs. 196 (11-7) Robert Morris | 3:00 PM | UW-Milwaukee Panther Arena, Milwaukee, WI | ESPN+ | 78 - 69 | 73% | | |
| 171 (8-9) Florida Atl vs. 194 (11-6) Rice | 1:00 PM | Eleanor R. Baldwin Arena, Boca Raton, FL | ESPN+ | 76 - 73 | 62% | | |
| 197 (6-11) Massachusetts vs. 170 (9-7) La Salle | 2:00 PM | Mullins Center, Amherst, MA | | 78 - 76 | 54% | | |
| 255 (6-11) Charlotte vs. 36 (13-4) Memphis | 3:00 PM | Halton Arena, Charlotte, NC | ESPN2 | 68 - 80 | 11% | | |
| 316 (3-13) IU Indianapolis vs. 166 (10-6) Cleveland St | 2:00 PM | Corteva Coliseum, Indianapolis, IN | ESPN+ | 67 - 75 | 18% | | |
| 330 (2-16) Green Bay vs. 215 (10-8) Youngstown St | 1:00 PM | Resch Center, Ashwaubenon, WI | ESPN+ | 69 - 77 | 22% | | |